Kladovo is a town and municipality located in the Bor District of the eastern Serbia, situated on the right bank of the Danube river.

In Serbian, the town is known as Kladovo, in Romanian Cladova, in German as Kladowo or Kladovo and in Latin and Romanised Greek as Zanes. In the time of the Roman Empire, the name of the town was Zanes while the fortifications was known as Diana and Pontes.

Emperor Trajan had a number of fortications constructed in the area during the Roman times, such as the well-known Trajan's Bridge (Pontes was built on the Serbian side, Theodora was built on the Romanian side). Later, Slavs founded a settlement that was named Novi Grad while Ottomans built a fortress here and called it Fethülislam. The present-day name of Kladovo is first recorded in 1596 in an Austrian military document.

The main business are the hydro-electric power plants of Đerdap: Iron Gate I and Iron Gate II. Other businesses began primarily to support the building and operation of the power plant, and the local folk. The population of the villages around Kladovo is mostly supported by the family members who work as guest-workers in the countries of western Europe, agriculture is a side activity more than an income-generating one.

Kladovo has a beach, Đerdap Archaeology Museum, Orthodox Church of Saint George and a pedestrian zone (Kladovo Skadarlija). Kladovo is on the European bicycle path and in 2016 about 16,000 cyclists passed through the town. As of 2017, the bus line Belgrade-Kladovo was the only one in Serbia which had bicycle carriers on the buses. The neighboring villages of Tekija and Brza Palanka also arranged beaches on the river. Other touristic attractions include the organized visits to the Iron Gate I power plant, local cuisine and the surrounding wine region between Kladovo and Negotin, the Negotin Krajina. In the 19th century, the wine produced here was shipped to Belgrade, Novi Sad, Budapest, Vienna, etc.

Donji Milanovac is a town in eastern Serbia, situated in the Majdanpek municipality, in the Bor District, located on the right bank of Lake Đerdap on the Danube. The management office of Đerdap national park is located in the town.

Donji Milanovac lies on remains of an 8000-year-old Mesolithic settlement of the Lepenski Vir, and of the Roman town of Taliata. Since the founding of the first settlement, Donji Milanovac was moved three times. It was originally established as a settlement called Banja which was moved some 10 km upstream, on the island of Poreč during the 17th century.

In 1830, due to frequent flooding, Prince Miloš ordered the town be moved to the nearest, right bank, so it was resettled 2 km downstream, at the mouth of river Oreškovica into the Danube. It became the first town in Serbia built by architectural planning. After construction of the "Đerdap I" hydroelectric power station in 1970, the town was moved again to its present location, another 6 km downstream, and the old site was completely flooded by the Lake Đerdap in 1971.

Lepenski Vir is an important Mesolithic archaeological site located 15 kilometers from Donji Milanovac. The latest radiocarbon and AMS data suggests that the chronology of Lepenski Vir is compressed between 9500/7200-6000 BC. There is some disagreement about the early start of the settlement and culture of Lepenskir Vir. But the latest data suggest 9500-7200 to be the start.

The Church of St. Nicholas is located in the centre of Donji Milanovac. It was built in 1840 thanks to captain Miša Anastasijević. Captain Miša's konak and Tenka's house have been proclaimed cultural heritage of Serbia. There is a monument to the 1912-1918 wars (Balkan Wars, First World War), and a mammoth sculpture. Another noted monument is the Roman Tabula Traiana.

In 1972 a hotel "Lepenski Vir" was built and the town beach was arranged. The area became a popular camping location as, due to the climate, there are no mosquitos. Donji Milanovac and the gorge are situated on the European bicycle corridor and the Đerdap highway, the shortest connection between Belgrade and Bucharest, Romania, and further with the Black Sea. The town also has a pier, which is today mostly used by the foreign river cruisers.